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contraindicate

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With approval, Shire said that Intuniv's labeling will contraindicate use in patients with a history of hypersensitivity to guanfacine or any of its active ingredients.
The 3-year survival of 8% for the group of patients who did not receive cyclosporine led the authors to conclude that severe renal dysfunction precluding the use of cyclosporine probably would contraindicate a second allogeneic transplant-or at least should lead to assessment of the role of new non-nephrotoxic immunosuppressive drugs, such as mycophenolate mophetyl.
LOUIS -- Covidien (NYSE:COV), a leading global provider of healthcare products, today announced that it will voluntarily contraindicate the use of its Optimark[TM] gadoversetamide injection, a gadolinium-based contrast agent (GBCA), in magnetic resonance imaging (MRI) procedures involving patients with severe renal impairment.
 
 
 
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