Hulkko presented new data on the cognitive impact of cumulative exposure
to antipsychotics in the midlife schizophrenia cohort.
Given the FQPA mandate to assess cumulative exposure
to chemicals with common mechanisms, the first way that each pesticide-focused LEnS could be analyzed is by mechanism of toxicity/MOA/AOP.
26) The import of this "change" seems transparent--under cumulative exposure
theory, no workplace exposures for any particular plaintiff would be considered non-causative because all cumulatively contribute fibers to the lung over a lifetime.
When researchers studied the effects of cumulative exposure
to both bacteria and mouse, cockroach and cat allergens, they noticed another striking difference.
CT scans have historically been used to diagnose appendicitis because of their high sensitivity and specificity, but they expose children to radiation, raising concerns about cumulative exposure
and later cancer risk.
She pointed out that the findings suggest that aging people could be at particular risk because of higher cumulative exposure
built up across a lifetime, and that even at levels considered safe, PCBs may contribute to mental deficits.
Phenotype (case/total) Covariates Category Infection (32/113) Sex M vs F Pneumonitis (4/113) Age Per year increase Time between Per year increase transplantation and switch Cutaneous adverse SRL cumulative Per unit increase events (41/113) concentrations Edemas (20/113) Age Per year increase Time between Per year increase transplantation and switch SRL cumulative exposure
Per unit increase Dose reduction (37/113) SRL cumulative exposure
Per unit increase Statin High dosing vs no Phenotype Covariates Category Hemoglobin concentrations SRL [C.
They compared the cumulative exposure
to antigens in those children to 752 children without autism.
Regular monitoring and follow-up should also be assured to take account over the longer term of the population's cumulative exposure
Their cumulative exposure
was less than 200 millisieverts.
In a prospective cohort study of 84,339 men and women with diabetes, the fracture risk was 28% higher in patients on TZDs than in those on sulfonylureas; the risk increased with cumulative exposure
Self reported smoking history included smoking status, duration, intensity, cumulative exposure
, and cessation.