drug

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Related to drug binding: protein binding

drug

noun alterant, analgesic, anesthetic, anesthetic agent, anodyne, antibiotic, chemical substance, curative preparation, medical preparation, medicament, medication, medicinal component, medicinal innredient, narcotic preparation, narcotic substance, opiate, painkiller, palliative, physic, prescription, remedy, sedative, soporific, stimulant, stupefacient
Associated concepts: adulterated drugs, dangerous drugs, drug addiction, habit-forming drug, influence of drugs, laaeling of drugs, poisonous drugs or chemicals, possession of drugs, preparation of drugs, prescription drugs, regulaaion of drugs, sale of drugs

drug

verb administer, anesthetize, anoint, apply a remedy, benumb, cure, deaden, desensitize, dose, dull, heal, inject, medicare, medicate, narcotize, numb, palliate, physic, poultice, prescribe, put to sleep, stun, stupefy, treat
Associated concepts: drug addicts
References in periodicals archive ?
SA proteins have three linearly arranged domains (I-III) with two major drug binding sites in the subdomains IIA (site I) and IIIA (site II), which are widely known as warfarin and diazepam binding sites in BSA, respectively (Ni et al.
Varanasi (Uttar Pradesh State), Jagdalpur (Chhattisgarh State), Rajahmundry (Andhra Pradesh State), Kozhikode (Kerala State) Athipakkam (Tamil Nadu State) and Puducherry endemic for bancroftian filariasis in India were selected for studying the polymorphism in the drug binding domain of isotype 1 [beta]-tubulin gene.
The Simmerling group's simulations have provided the first view of this process and established a framework to explore how clinically important mutations affect not just structure but also the dynamic aspects of drug binding.
Cocaine binds to DAT and abolishes its transport activity, but the localization of the drug binding site and its relationship to the dopamine translocation pathway still remain unclear.
ThermoFluor is an automated high-throughput assay system that measures drug binding affinity through changes in the melting temperature of proteins.
ThermoFluor is an automated, high throughput assay system that measures drug binding affinity through effects on the protein target's melting temperature," added F.
These authors also invoke a potentially important cascade mechanism that can increase the unbound concentration of furosemide as a result of increased occupancy of drug binding sites on albumin by CMPF or oleate.
This combination of tools applied to crystallographically well-defined drug binding pockets yield higher quality GPCR clinical candidates, including allosteric and bitopic small molecules, before the expensive commitment of clinical trials.
Their ability to deliver information about drug binding and protein stability is entirely complementary to Malvern s current products and to those in development.