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These biased ligands provide an enhanced level of drug specificity which allows enhanced efficacy or decreased side effects to be designed into the drug candidate.
The technology covered by this patent enables Cadus to identify drugs that selectively inhibit or potentiate interlinked signaling pathways, a capability which has important implications for enhancing drug specificity and reducing side effects significantly," said Philip N.
These biased ligands selectively turn on or off individual pathways, and in so doing provide an enhanced level of drug specificity.