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Furthermore, we analyzed levels of oxidative stress, as well as cyclic adenosine 3',5'-monophosphate response element-binding (CREB) protein phosphorylation and immediate early gene (IEG, including Arc, c-fos, and Egr1) expression levels using Western blot analysis.
The increase in stress factors, neurotrophic and early genes in response to stress as a condition of mild stroke may indirectly prevent lethal ischemic insult by opening the adenosine triphosphate (ATP)-sensitive potassium channels [14].
Although the direct association between HPV infection and inflammation is controversial, transgenic mouse models, expressing the early genes from HPV 16 under the control of the human keratin 14 promoter, have shown that HPV-induced lesions release the chemokine CCL2 which enhances macrophage recruitment into tumours via CCR2.
As in the case of H3 the combination of phosphorylation, O-GlcNAc modification, acetylation and methylation in silico controls the expression of immediate early genes (Kaleem et al.