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Irish-born William Campbell and Japan's Satoshi Omura won half of the prize for discovering avermectin, a derivative of which has been used to treat hundreds of millions of people with river blindness and lymphatic filariasis, or elephantiasis.
The serious side effects of Loa loa and the difficulty of rapidly quantifying Loa levels in patients before treatment make it too risky to broadly administer IVM, representing a major setback in the efforts to eradicate river blindness and elephantiasis.
Lymphatic filariasis, commonly known as elephantiasis, is a parasitic disease that is transmitted to humans by the bite of a mosquito.
Ailments such as intestinal worms, river blindness and elephantiasis are classed as "neglected tropical diseases" (NTDs), and the most affected people are those living in distant rural areas or slums.
He has also acted as an advisor to the World Health Organisation on disease control programmes for sleeping sickness, river blindness, elephantiasis and guinea worm.
The World Health Organization reports that more than 120 million people suffer from lymphatic filariasis, commonly known as elephantiasis.
Significantly high level of IL-10 in CFA-negative hydrocele cases also correlates with the amicrofilaraemic condition in our study as described by Dimock et al (12) where they have shown greater T-cell proliferation and interleukin-10 (IL-10) production in amicrofilaremic patients with hydrocele or elephantiasis than in amicrofilaremic or microfilaremic asymptomatic persons.
Scrotal elephantiasis is a condition characterized by massive scrotal lymphedema with gross genital deformation.
Rasim SarybaE-, 61, an elephantiasis patient, is a symptom of a variety of diseases, where parts of a person's body swell to massive proportions, haven't found any remedy for his illness.
13 Cases of disfiguring and disabling genital swelling also have been reported, including scrotal elephantiasis.
5 billion of the world's most impoverished people, including 800 million children, NTDs can cause sight loss and elephantiasis.