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8, left ventricular end-diastolic volume decreased 18 mL, and ejection fraction increased 14. Resting heart rates were decreased (from 71 to 63 beats per minute [bpm]) as well as heart rates during standardized submaximal work (from 117 to 109 bpm), Cardiac catheterization revealed no change in resting left ventricular ejection fraction, left ventricular end-diastolic pressure, or left ventricular end-diastolic volume, all of which further suggested the importance of peripheral adaptation in skeletal muscle. |
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