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5 mg/dl, n (%) Data are presented as mean [+ or -] SD and numbers (percentages) * unpaired t test and Chi-square test LVEF--left ventricular ejection fraction, LVVs--left ventricular end-systolic volume, NT-pro BNP N--terminal pro-B-type natriuretic peptide, sPAP--Systolic pulmonary arterial pressure Q-left time, the time from the onset of the Q-wave on the surface ECG to the onset of the regional systolic motion of left ventricle (evaluated by TDI).
Patients with the CRT device turned on also had significantly improved left ventricular function, as reflected in their ejection fraction and end-diastolic and end-systolic volumes.
LVEF, left ventricular ejection fraction; LVEDP, left ventricular end-diastolic pressure; LVEDVI, left ventricular end-diastolic volume index; LVESVI, left ventricular end-systolic volume index; PAP mean, mean pulmonary arterial pressure; PAP diast.
Reduction of end-systolic volume was 3-times larger in the C-Cure group compared to the control group (from 171 plus or minus 9 to 150 plus or minus 9mL, and from 167 plus or minus 8 to 159 plus or minus 8mL, p=0.
Left ventricular end-systolic volume index was measured echocardiographically after 1 year.
NYSE MKT: MSTX) today announced that, in a placebo-controlled, nonclinical model of chronic heart failure, MST-188 demonstrated a statistically significant improvement in numerous parameters of heart function, including left ventricular ejection fraction and end-systolic volume, stroke volume and cardiac output.

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