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Related to endocrine therapy: tamoxifen
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Given the importance of adjuvant endocrine therapy to patient survival and quality of life, "clinicians are encouraged to inquire diligently about treatment compliance and treatment-related adverse effects, and to pursue interventions known to mitigate adverse effects and enhance adherence," the guideline says.
American Society of Clinical Oncology clinical practice guideline: update on adjuvant endocrine therapy for women with hormone receptor-positive breast cancer.
Modulation of cancer endocrine therapy by melatonin: a phase II study of tamoxifen plus melatonin in metastatic breast cancer patients progressing under tamoxifen alone.
Immunohistochemical evaluation of estrogen receptor status in benign prostatic hypertrophy and in prostate carcinoma and the relationship to endocrine therapy.
What's different about this one is it compares a baseline of breast cancer patients not receiving endocrine therapy," noted Dr.
Alternatively, patients who begin an AI but discontinue it before 5 years have elapsed can consider taking tamoxifen until a total of 5 years of endocrine therapy accrue.
Results from the Austrian Breast & Colorectal Cancer Study Group Trial 12 (ABCSG-12), demonstrated that Zometa(R) improved disease-free and recurrence-free survival in 1,801 premenopausal women with early breast cancer receiving adjuvant (post-surgery) endocrine therapy with goserelin in combination with anastrozole or tamoxifen.
Does endocrine therapy for the treatment and prevention of breast cancer affect memory and cognition?
Though roughtly half carry estrogen receptors that in fact bind with estrogen, these cancers apparently do not need or use the estrogen and therefore "have not responded at all well to any endocrine therapy.
Study Demonstrates Ability of PAM50 Assay to Indicate Risk of Recurrence in Women with HR+ Early-Stage Breast Cancer Treated with Endocrine Therapy Alone
The next phase of the work will complete analysis for the remaining patient cohort and investigate the profiling of CTCs' biology sequentially over time to support treatment decisions in relation to HER2 directed therapy, chemotherapy, and endocrine therapy.
Tenders are invited for Providing Medicines in the Endocrine Therapy Medicinal Products.