The stage-dependent inhibitory effect of porcine follicular cells
on the development of preantral follicles.
cAMP is considered the primary second messenger in thyroid follicular cell
growth and maintenance (Medina and Santisteban 2000; Richards 2001).
The diagnoses were diffuse large cell lymphoma (106), follicular cell
lymphoma (81), and mantle cell lymphoma (21).
From the follicular cell
, the iodide moves across the apical membrane, transported by pendrin protein (Yoshida et al.
RET is highly expressed in thyroid parafollicular or C cells but not in follicular cells
, where it can be activated by chromosomal rearrangement known as RET/PTC rearrangement.
Concerning nonneoplastic lesions in mice, increases of thyroid gland follicular cell
hyperplasia occurred in all THC groups, and increases of forestomach hyperplasia and ulcers occurred in THC groups of male mice; yet, no THC-related tumors were observed to progress from these toxic lesions.
A core was considered positive if any thyroid follicular cell
was immunoreactive, given the smaller number of follicular cells
in the core.
Maturation of ovarian follicles: actions and interactions of pituitary and ovarian hormones on follicular cell
Mechanisms of action of agents that cause thyroid follicular cell
tumors in experimental animals have been studied extensively and include both genotoxic and nongenotoxic processes; these mechanisms have been specifically addressed in several papers in Capen et al.
Recently, Medicare expanded coverage for PET technology to include the staging of recurrent breast cancer, as well as restaging of recurrent or residual thyroid cancers of follicular cell
23-25) Recently, Kondo et al (24) reviewed the pathogenetic mechanisms of thyroid follicular cell
neoplasia and found mutations of BRAF (29%- 69%), RET (13%-43%), and RAS (0%-21%) are most commonly seen in adult papillary thyroid carcinoma; RET rearrangements are more prevalent in adult tumors associated with previous radiation exposure.
Indeed, the problems and controversies that exist in the classification of thyroid carcinomas of follicular cell
origin have an impact on the prognosis and therapy of our patients as well as on the development of robust cutting-edge research aimed at better outcomes and quality of life.