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Related to foot processes: Glomerular podocytes
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Foxc2 knockout mice retain an immature phenotype and do not have organized foot processes and SD.
34) Proteinuria also may occur without mislocalization of the SD and in the presence of perfectly normal foot processes by morphology, as shown in 3 different models of proteinuria, one due to injection of antibodies to VEGF or soluble VEGF receptor 1, the second due to genetic deletion of nephrin expression, and the third resulting from deletion of the [[alpha].
42 During effacement, cytoskeletal rearrangement moves the foot processes along the GBM.