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Below the maximum tolerated dose, diazinon impaired neuritic outgrowth in the forebrain and brainstem, evidenced by a deficit in the ratio of membrane protein to total protein. Labeling of inclusion bodies and some intracytoplasmic staining was notable from the forebrain (prosencephalon) to the mesencephalon (Figure, panel A). 4) At week 5, the mesenchyme, which covers the caudal surface of the forebrain, proliferates with the surface ectoderm to form the frontonasal process. |
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