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But with gallstones, thought to affect as many as one in six people, with famous sufferers including the likes of Eric Clapton and the Dalai Lama, it's not quite that simple.
If raised BMI truly is a causal factor in the development of gallstone disease, genetic variants that increase BMI would be expected to also increase risk of gallstone disease," said Dr.
Shortly after its introduction in the 1980s, laparoscopic cholecystectomy (LC) became the surgical treatment of choice for symptomatic gallstones.
Researchers found that overweight children were twice as likely to develop gallstones, while moderately obese children have a four times higher risk of developing gallstones and extremely obese children are six times as likely to have gallstones.
Women who had gallstones at the first ultrasound and those with a history of gallstones were excluded.
The risk of gallstones after 5 years of follow up was significantly lower in the most active group compared with the inactive group, regardless of sex, after adjusting for covariates (HR=0.
This defect is due to mutation of a gene in the liver -- identified as Adenosine Triphosphate Binding Casette- transporter Gene ( ABCG8) -- resulting in excess excretion of cholesterol into the bile, causing cholesterol gallstones," Dr Reddy said on Thursday.
Gallstone disease is an ailment of the gastrointestinal tract afflicting approximately 6.
She was a previously fit and healthy woman who was undergoing a routine procedure to have gallstones removed and they had every reason to expect she would make a normal recovery.
Results: Allele frequencies of 388 G were 45 per cent in gallstone cases and 44 per cent in controls with no statistical significance.
prompted concerns about a possible link between Xenical[R] (orlistat, Roche Laboratories) and gallstones in patients of all ages.
Up to one in 11 patients admitted to hospital with gallstone disease has acute cholangitis - inflammation of the bile ducts - according to Drug and Therapeutics Bulletin (DTB).