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Phenols and indoles absorbed in the large intestine are then detoxified by conjugation with glucuronic acid in liver and excreted via urine as glucuronides.
The typical steroidal saponin molecule has an aglycone or non-saccharide portion (sapogenin) attached to one or more sugar chains containing glucose, galactose, xylose, arabinose, rhamnose or glucuronic acid (HOSTETTMANN & MARSTON, 1995; WINA et al.
Samples may also have to be hydrolysed to release steroid metabolites from their glucuronic acid conjugates, usually by means of the enzyme [[beta].
2,3,6-8 In an enzymic activity, the sugars in the syrup turn into glucose and fructose, and the glucose oxidase enzyme changes glucose into glucuronic acid and hydrogen peroxidase.
The bacteria that inhabit our intestinal tract (also called our intestinal flora or microbiome) play a major role in our health, and not just our intestinal health; gut bacteria have a profound effect on the rest of our bodies as well For example, one of the key ways the body gets rid of cancer-causing substances such as excess estrogen or fat-soluble toxins like pesticides and solvents is by binding the toxin in the liver to a molecule called glucuronic acid and then excreting it in bile.
Heme is converted to unconjugated bilirubin, which is secreted into the plasma, bound to albumin, and transported to the liver, where it is conjugated to glucuronic acid and excreted in bile.
The major pathways of VA biotransformation include b-oxidation and conjugation with glucuronic acid, and only a smaller part of the metabolism occurs via CYP2D6 isoenzyme-dependent oxidation and desaturation reactions (4).
This enzyme attaches glucuronic acid to testosterone, making it more likely to be excreted through urine.
The biopolymer is a glycosaminoglycan and is comprised of repeating disaccharide units that contain a glucuronic acid and N-acetyglucosamine units.
Hyaluronic acid contains glucuronic acid (GlcUA), a representative biogenic carboxylic, and GlcNAc, a representative biogenic amine.
In nature, the enzyme cleaves glucuronic acid from hemicellulose and, in so doing, helps disassemble plant cell walls.
N-desvenlafaxine-glucuronide is an end product of a 2-step metabolic reaction that starts with oxidation by CYP 3A4 to produce N-desvenlafaxine, which is conjugated with glucuronic acid to create N-desvenlafaxine-glucuronide.