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The show, Going Ape, is to be screened on BBC1 next Wednesday.
Mel Gibbon then took the starring role in Braveheart before Madonna was sent up by a chimp going ape in her trademark cone-shaped bra.
She's going ape in her quest to show that we're all very much a part of the animal kingdom.
Everybody's already going ape over the virtual gig between Madonna and Gorillaz, the animated band co-created by Blur's Damon Albarn.