Control of proliferation and differentiation of ovine granulosa cells
by insulin-like growth factor-I and follicle stimulating hormone in vitro.
For statistical purposes, the patient sera were divided into five main groups: controls, serous, mucinous, granulosa cell
, and miscellaneous.
Features of follicle atresia and cystic formations were described (Figure 1): cell pyknosis, interruption of the basement membrane and thecal layers' disruption, reduction of granulosa cells
layers, presence of elongated epithelioid cells in the surface lining the follicle wall.
In vitro exposure of porcine granulosa cells
to the phytoestrogens genistein and daidzein: Effects on the biosynthesis of reproductive steroid hormones.
2009), and miRNAs demonstrate spatio-temporal expression in oocytes, granulosa cells
(GCs), cumulus cells, and preimplantation embryos (Abd El Naby et al.
Intermediate filamentous proteins in adult granulosa cell
tumors: an immunohistochemical study of 25 cases.
Of these 36( 76 %)were granulosa cell
tumours (adult 33, juvenile 3), 7 were labeled as sertoli leydig cell tumours (15%), 3 as thecoma/ fibroma group (7%) and only one case was labeled as microcystic stromal tumour of the ovary (2%).
Effect of insulin-like growth factor I and its interaction with gonadotropins on in vitro maturation and embryonic development, cell proliferation, and biosynthetic activity of cumulus-oocyte complexes and granulosa cells
In another study histological observations of folliculogenesis and follicular atresia in immature female rats (0-35 days old) were studied; after day 30 numerous primary follicles and atretic follicles were observed in the ovaries, antrum grew larger in the follicles where oocyte disappeared and granulosa cell
layer became thin.
tumors, which are a sex cord-stromal tumor group, can be divided into adult granulosa cell
tumor and juvenile granulosa cell
tumor (JGCT) subtypes (1).
1999), we found that in a 1:1 co-expression of mER[beta]2 and mER[beta]1 in HepG2 cells, which represents the levels found in ovarian granulosa cells
, the transactivation activity of mER[beta]2 and mER[beta]1 is significantly reduced compared to that of mER[beta]1 alone.
In vitro, high concentration of prolactin equivalent to those seen in lactation, inhibit progesterone production by human granulosa cells
even in the presence of high FSH and LH.