Key words: Paroxysmal nocturnal hemoglobinuria
, eculizumab, complement, hemolytic episode
com/research/806dd2/paroxysmal_nocturn) has announced the addition of new report "Paroxysmal Nocturnal Hemoglobinuria
(PNH) Therapeutics - Pipeline Assessment and Market Forecasts to 2019" to their offering.
1) Abstract 3166, entitled "Uncontrolled Complement Activation and the Resulting Chronic Hemolysis As Measured by LDH Serum Level At Diagnosis As Predictor of Thrombotic Complications and Mortality in a Large Cohort of Patients with Paroxysmal Nocturnal Hemoglobinuria
(PNH)," presented by Jong Wook Lee at the 53rd American Society of Hematology (ASH) Annual Meeting and Exposition, December 12, 2011.
Nasdaq: ALXN) today announced the presentation of research that provides further insight into the clinical consequences of paroxysmal nocturnal hemoglobinuria
(PNH), and positive impact of Soliris[R] (eculizumab) therapy on long-term outcomes.
(not hematuria), unconjugated bilirubinemia (3.
European Union, Japan and other countries as the first and only treatment for patients with paroxysmal nocturnal hemoglobinuria
(PNH), a debilitating, ultra-rare and life-threatening blood disorder, characterized by complement-mediated hemolysis (destruction of red blood cells).
Rare: Cancer of the Pancreas, Hemoglobinuria
, Crush Syndrome, Melanoma, Alkaptonuria
A New York Post report said that Soliris, made by Alexion Pharmaceuticals, is given intravenously to treat paroxysmal nocturnal hemoglobinuria
, or PNH, a rare disorder in which the immune system destroys red blood cells.
has announced positive data from the 26-week extension of the AEGIS study, an open-label registration study examining Soliris (eculizumab) for the treatment of Japanese patients with paroxysmal nocturnal hemoglobinuria
The pharmaceutical company derives all of its revenue from Soliris, which treats paroxysmal nocturnal hemoglobinuria
Soliris was approved in the United States and European Union in 2007 as a treatment for patients with paroxysmal nocturnal hemoglobinuria
("PNH"), a rare, debilitating and life-threatening blood disease.
Reported causes of intravascular hemolysis that result in renal hemosiderosis are mechanical hemolysis (ie, from a dysfunctional valve replacement), paroxysmal nocturnal hemoglobinuria
, and sickle cell anemia.