lesion

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Related to high-grade squamous intraepithelial lesion: HSIL

lesion

injury or loss. In the civil law jurisdictions the word is often used in the context of an ‘unfair’ loss, as where an adult takes advantage of a minor or someone purchases something for much less than it's worth.

LESION, contracts. In the civil law this term is used to signify the injury suffered, in consequence of inequality of situation, by one who does not receive a full equivalent for what he gives in a commutative contract.
     2. The remedy given for this injury, is founded on its being the effect of implied error or imposition; for in every commutative contract, equivalents are supposed to be given and received. Louis. Code, 1854. Persons of full age, however, are not allowed in point of law to object to their agreements as being injurious, unless the injury be excessive. Poth. Oblig. P. 1, c. 1, s. 1, art. 3, Sec. 4. But minors are admitted to restitution, not only against any excessive inequality, but against any inequality whatever. Poth. Oblig. P. 1, c. 1, s. 1, art. 3, Sec. 5; Louis. Code, art. 1858.
     3. Courts of chancery relieve upon terms of redemption and set aside contracts entered into by expectant heirs dealing for their expectancies, on the ground of mere inadequacy of price. 1 Vern. 167; 2 Cox, 80; 2 Cas. in Ch. 136; 1 Vern. 141; 2 Vern. 121; 2 Freem. 111; 2 Vent. 359; 2 Vern. 14; 2 Rep. in Ch. 396; 1 P. W. 312; 1 Bro. C. C. 7; 3 P. Wms. 393, n.; 2 Atk. 133; 2 Ves. 125; 1 Atk. 301; 1 Wils. 286; 1 Wils. 320; 1 Bro. P. 6. ed. Toml. 198; 1 Bro. C. C. 1; 16 Ves. 512; Sugd. on Vend. 231, n. k.; 1 Ball & B. 330; Wightw. 25; 3 Ves. & Bea. 117; 2 Swanst. R. 147, n.; Fonb. notes to the Treatise of Equity, B, 1, c. 2, s. 9. A contract cannot stand where the party has availed himself of a confidential situation, in order to obtain some selfish advantage. Note to Crowe v. Ballard. 1 Ves. jun. 125; 1 Hov. Supp. 66, 7. Note to Wharton v. May. 5 Ves. 27; 1 Hov. Supp. 378. See Catching bargain; Fraud; Sale.

References in periodicals archive ?
Test characteristics of specific p16 clones in the detection of high-grade squamous intraepithelial lesions (HSIL).
Factors Influencing Misinterpretation of High-Grade Squamous Intraepithelial Lesion Slides in the Interlaboratory Comparison Program in Cervicovaginal Cytology (PAP) Education and PAP Proficiency Test Programs (Nonlinear Mixed-Model Summary) PAP Education No.
The odds ratios for progression to squamous intraepithelial lesions or HSIL were higher for oncogenic HPV-positive women than for those with atypical squamous cells in which a high-grade squamous intraepithelial lesion cannot be ruled out (ASC-H).
The 2001 Bethesda system sought to eliminate the confusion around an ASC-US diagnosis, by better defining criteria, encouraging downgrading to negative for intraepithelial lesion and malignancy (NILM) when possible, and introducing a new atypical category--atypical squamous cells of a high-grade squamous intraepithelial lesion cannot be ruled out (ASC-H).
When asked which interpretive rates were felt to not be useful, most comments included relatively rare but significant interpretations such as atypical glandular cells, atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion (ASC-H), and cancer.
CLIA '88 also mandates review of all Pap tests interpreted as NILM (NILM Pap tests) from the last 5 years for a patient with a current Pap test that shows a high-grade squamous intraepithelial lesion (HSIL) or carcinoma (HSIL+).
Formalin-fixed, paraffin-embedded tissues included 56 anorectal biopsy or surgical resection specimens with the following tissue diagnoses: 29 low-grade squamous intraepithelial lesion (encompasses condyloma, mild dysplasia, and anal intraepithelial lesion 1), 15 high-grade squamous intraepithelial lesion (encompasses moderate dysplasia, anal intraepithelial lesion 2, severe dysplasia, anal intraepithelial lesion 3, and carcinoma in situ), and 12 invasive squamous cell carcinoma.
ASCH would indicate cytologic changes that suggest high-grade squamous intraepithelial lesion but lack definitive criteria.
The follow-up results were categorized as negative (negative for intraepithelial lesion or malignancy, atypical squamous cells of undetermined significance [ASCUS]/atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion [ASCH] with no follow-up biopsy, negative biopsy result, ASCUS/ASCH results followed by a negative biopsy result), low grade (low-grade squamous intraepithelial lesion/CIN I proven by follow-up biopsy or excision), high grade (HSIL, CIN II and CIN III proven by follow-up biopsy or excision), and carcinoma (including squamous cell carcinoma and adenocarcinoma).