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He said tumor cells grow really fast, but the blood vessels that feed them oxygen cannot grow fast enough, so tumor cells become hypoxic, adding that the tumor cells have to develop some sort of mechanism to survive under hypoxic stress, and that's HIF-1 alpha.
virginica adults had similar aerobic metabolic rates; however, differences may exist in the metabolic pathways and rate used during hypoxic stress.
89) Placental erythroblastosis may require severe, ongoing hypoxic stress of at least days', if not weeks', duration, and stillborn fetuses, dying of hyperacute etiologies, characteristically do not exhibit normoblastemia.
4) A more recent study by Papas suggests a higher threshold is necessary to avoid zero hypoxic stress (125x[10.