The gene immunoadjuvant
program complements our existing technology and will further enhance our dominant position in the field of optimized DNA vaccines.
Brooke Army Medical Center, focuses on the concept that AE37 vaccine's Ii-Key hybrid technology "has improved the potency of the AE37 vaccine to the point where it is capable of inducing immune responses even without immunoadjuvant
," and that "preclinical and early clinical trials of the AE37 show potential promise for this CD4+ T-cell-eliciting vaccine in the adjuvant treatment of breast cancer.
The LSAI technology involves injecting a tumor with an infrared absorbing dye and an immunoadjuvant
, followed by treatment with an infrared laser.
Molecular Therapy published a paper describing that co-delivery of Inovio's DNA-based interleukin (IL)-28B immunoadjuvant
and an optimized SynCon(TM) DNA vaccine using its proprietary electroporation technology significantly enhanced antigen-specific killer T-cell responses in rhesus monkeys.
Since the identification of a single therapeutic with both immunoadjuvant
capabilities plus the ability to enhance maturation and mobility of stem cells might be of significant therapeutic significance, the Company plans future studies to explore this opportunity in more detail.
The treatment consists of the co-injection of an infrared absorbing dye and an immunoadjuvant
directly into a tumor, followed by illumination with an infrared laser.
galactochitosan and a photosensitive infrared dye
The novel treatment to which Xytronyx has a worldwide exclusive license, consists of the co-injection of a photosensitizing drug (infrared absorbing dye) and an immunoadjuvant
directly into a tumor followed by illumination with an infrared laser.