inbred

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Oh sure, if you've got bad genes, you fix it in the population, but if you want to fix a good gene, you inbreed.
From this perspective, and all else being equal, populations or species that persistently inbreed should exhibit lower levels of inbreeding depression upon close inbreeding than populations or species that regularly outcross.
Introducing artificial mutations into mice enhanced the value of plain generic inbreeds as subjects for study.