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inhibitor
(redirected from indinavir)

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See: deterrent


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John’s Wort affects pathways in the liver, so it can interfere with infection-fighting drugs like indinavir (used to treat HIV) and cyclosporine (used to prevent organ transplant rejection).
Early data on initial therapy demonstrated potent but transitory antiviral effect with ritonavir and indinavir monotherapy and was followed by several seminal papers evaluating a regimen consisting of a PI combined with two nucleosides designed for maximal suppression of HIV replication [1].
After a 60-year overview of the history and evolution of synthesis of natural products, sections on comparative design cover classics in terpenes and alkaloid synthesis, with an additional section on miscellaneous targets such as palytoxin, brevetoxin B, and indinavir.
 
 
 
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