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The course of disease may be affected by the ingested infective dose, host factors, and virulence of S. The infective dose for gastrointestinal symptoms in healthy individuals is unknown, but for predisposed persons, septicemia can presumably occur with doses of fewer than 100 organisms. Although much of the vibrio did remain free in the filtered water, their number often diminished enough to fall short of an infective dose, estimated at [10. |
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