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In many forms of epilepsy, loss or malfunction of inhibitory nerve cells within the hippocampus plays a critical role.
Klaus Funke (Department of Neurophysiology) have now shown for the first time that an artificial cortex stimulation specifically changes the activity of certain inhibitory nerve cells as a function of the stimulus protocol used.
17] As the pain fibers grow and make new connections, the pain spreads and persists while the inhibitory nerves which serve to dampen messages of pain are slowly destroyed and the neurochemical systems related to control of EAAs, serotonin, norepinepherine, opiates and GABA become dysfunctional.

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