Other than typical localizations, sporadic cases exist involving demyelinated plaques in the cervical spinal cord, midbrain, medulla, internal capsule
, and cerebral peduncle, even cases of MS not explainable by anatomical evidence have been reported (6,7).
CT scan of the head showed a hypodense area in the posterior limb of the right internal capsule
The nucleus accumbens, internal capsule
, und cg25 all appear to be connected to the medial forebrain bundle.
For OCD and treatment-resistant depression; a further psychiatric disorder which Medtronic is currently exploring with Reclaim DBS therapy in a multi-center randomized clinical trial; the anatomical target in the brain is the anterior limb of the internal capsule
(AIC), and more specifically, a region sometimes referred to as the ventral capsule/ventral striatum (VC/VS), which is a central node in the neural circuits believed to regulate mood and anxiety.
MR patterns consist of small-size infarcts, involving basal ganglia, internal capsule
and brainstem (Figure 1).
Repeat CT scan of the brain showed new bilateral temporo-occipital hypodensity more on the left side and a probable right middle cerebellar and left thalamic internal capsule
For example, a stroke in the internal capsule
might interrupt sensory fibers, motor fibers, and fibers involved in other functions, all running very close to one another.