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Related to lethal mutation: neutral mutation, Conditional lethal mutation

MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t.

References in periodicals archive ?
1994) showed that even lethal mutations could be very difficult to purge through moderate self-fertilization, if genomic mutation rate, U, and inbreeding depression are sufficiently high.
If these data on chlorophyll deficiencies are representative of lethals in general, they indicate that genomic lethal mutation rates may be more than an order of magnitude higher in trees than in annual plants (Klekowski and Godfrey 1989).
Small, isolated founder populations such as these are expected to carry fewer harmful recessive mutations than the general population, because lethal mutations are more effectively selected against by natural selection in small populations.
But both lethal mutations, most of which act early in embryonic development, and sterility mutations are hard to observe phenotypically.
The rates of spontaneous lethal mutations estimated by Mukai et al.
The background genome was modeled after the method of Kondrashov (1985), and simplified by considering only lethal mutations (Lande et al.
Estimates of mutational variances and covariances obtained from mutation accumulation against a balancer will be disproportionately influenced by the first class as, in this case, recessive mutations are virtually sheltered from natural selection (lines carrying lethal mutations were usually excluded from analyses).
most new deleterious mutations had a small deleterious effect, although there was a peak of lethal mutations (Simmons and Crow 1977).
A number of theoretical models have indicated that the genetic load due to recessive lethal mutations is rapidly purged from a population following even a small amount of inbreeding, whereas that component of the load due to mildly deleterious mutations or to polygenic mutations is difficult to purge (Lande and Schemske 1985; Charlesworth and Charlesworth 1987; Charlesworth et al.
Although lethal mutations have been documented for Mimulus (Kiang and Libby 1972; Willis 1992), they likely do not play an important role in inbreeding depression.