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metabolize |
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Further, they have confirmed that CYP2C76 metabolizes drugs and is frequently expressed in the liver. Researchers analyzed blood samples from roughly 2,000 Costa Rican heart attack survivors and 2,000 similar people without heart disease--to see whether they had genes that result in the fast or slow version of the enzyme that metabolizes caffeine (cytochrome P450 1A2). Phase 1 trials evaluate safety, tolerability and how an experimental drug metabolizes in humans. |
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