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The minimum effective concentration of L-DOPA ranges from 3 to 12 [micro]mol/L and is equivalent to the range of 3 to 15 [micro]mol/L reported by Nutt and Woodward [4].
The mean plasma levels of FG-3019 varied from patient to patient but were above the minimum effective concentration determined in animal models of fibrosis for approximately 13 days and 23 days for the 3.

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