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| The PrP WB signature in these cases differed from the known scrapie profile; the classic 3-band WB pattern was replaced by a multiband pattern with a prominent band of low molecular mass ([approximately equal to] 12 kDa). We attributed that largely to the removal of high molecular mass organic matter, which represented a significant fraction of TCF effluent but not ECF effluent. Maintenance of a restriction on the relative mass distribution in the specifications of carrageenan for food use provides protection against the adverse effects of carageenans (sp) of low relative molecular mass. |
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