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Mutation |
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MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t. |
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To optimize the assay, we performed PCR-based H274Y mutagenesis of the N1 fragment of the H5N1 virus (primers on request). We used the QuickChange site-directed mutagenesis kit from Stratagene (La Jolla, CA, USA) and the following primers: 5'-GGTTCTGAATCAGTCTGAAATGCCTTCATTAAK4GC-3 and 5'-AATGAAGGCATTTCAGACTGATTCAGAACCAAACC-3'. Nadeau is part of the International Mouse Mutagenesis Consortium, an effort to develop a mutant mouse strain for each of the 30,000 functional genes in the mouse genome. |
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mutagenesis
