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5-9) Malignant peripheral nerve sheath tumors usually arise in major nerve trunks, such as the sciatic nerve, brachial plexus, and sacral plexus. Andrianova and colleagues examined "direct" stimulation, where the electrodes were placed over the muscle, and "indirect" stimulation, where they attempted to stimulate the nerve trunk supplying the muscle. The accumulation of lead in the endoneurial space in a peripheral nerve trunk may affect the Schwann cells at an early stage. |
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