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BSE has been linked with new variant Creutzfeldt-Jakob disease, the human version of the fatal brain-wasting ailment that has killed some 80 Europeans since the mid-1990s, mostly in Britain.
Since 1995 in the United Kingdom (England, Scotland, Northern Ireland, Wales, the Isle of Man, and the Channel Islands), new variant Creutzfeldt-Jakob disease (nvCJD) has been associated with the consumption of meat from cattle infected with bovine spongiform encephalopathy (BSE), commonly known as mad cow disease.
Soto is also the originator of several landmark patents in the field of new variant Creutzfeldt-Jakob Disease.
The subsequent spread of this disease into humans as new variant Creutzfeldt-Jakob disease (CJD) remains one of the unsolved emerging infectious disease mysteries of the 20th century.