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antibiotic |
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The drugs tested were amikacin, ampicillin-sulbactam, aztreonam, cefepime, cefotaxime, ceftazidime, ceftriaxone, ciprofloxacin, gentamicin, imipenem, levofloxacin, meropenem, ofloxacin, piperacillin, piperacillintazobactam, tetracycline, tobramycin, and trimethoprim-sulfamethoxazole. Goldblatt et al showed that topical ofloxacin was more effective than oral amoxicillin/clavulanate when S aureus or P aeruginosa was present (although the two were equal when S pneumoniae, M catarrhalis, or H influenzae was present). The previously recommended fluoroquinolones (ciprofloxacin, ofloxacin, or levofloxacin) can still be used in certain cases, provided that a culture is run, or a test for cure, and the patient returns for followup, and re-treatment with a different drug if necessary. |
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