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Six of 14 patients with perisinusoidal fibrosis and 6 of 13 with portal fibrosis showed improvement.
Lipid accumulation in Ito ceils and bile duct hyperplasia accompanied by portal fibrosis were correlated to age, whereas no changes were associated with either sex or season (summer vs.
The findings of percutaneous liver biopsy were consistent with drug-induced cholestatic hepatitis, revealing portal and lobular inflammatory infiltrates with excess of eosinophils, mild portal fibrosis, central and focal necrosis, and macrovesicular fatty infiltration (30%).
Patients with only portal fibrosis (minimal fibrosis) should have a high inflammatory score.