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Clinical application of array-based comparative genomic hybridization for the identification of prognostically important genetic alterations in chronic lymphocytic leukemia.
We now have the ability to do robust, 'next-generation' gene sequencing on blood and tissue samples, with tremendous possibilities in terms of what we can learn diagnostically, prognostically, therapeutically," says Candace Johnson, PhD, Deputy Director of Roswell Park and co-leader of three recently launched clinical research studies that rely on CPM resources.
As well as its diagnostic utility, EVLW measurement may have utility both prognostically in predicting survival in those admitted to ICU (64), and therapeutically by providing a measurement against which to titrate fluid balance.
Water budgets for these regions are difficult to model prognostically without significant a priori knowledge of irrigation practices and groundwater table fluctuations.
10) Prognostically, there is little that can be offered to the patient and studies revealed this to be one of the greatest challenges for the individual.
maltophilia, which was previously not regarded as prognostically significant, may have a real impact on the progression of CF in patients," said Valerie Waters of the Hospital for Sick Children in Toronto.
For others, an attempt almost reignites their natural fear of death, a much more prognostically favorable situation.
Excisional biopsy is the preferred method for melanocytic lesions, when possible, because partial biopsy may sample nondiagnostic areas or miss the prognostically worse portion of the lesion.
5) Literature indicates that CTC enumeration is prognostically important and allows oncologists to monitor patients for disease progression and malignancy relapse.
11) In the 3 subjects who lost weight the loss was composed mostly of LBM, and this is well known to be prognostically unfavourable.
Of significance, CA 15-3 levels were found to be prognostically useful in two reports [11,12] in lymph node-negative breast cancer patients, one of the subgroups of patients for whom new prognostic factors are most urgently required.
Cavitation is another prognostically helpful feature, as it typically portends resolution with treatment.