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Nerve cells in the dorsal raphe nucleus connect to the dopamine reward system, but many of the pathways are rich in serotonin.
When the pathway between the prefrontal cortex and the dorsal raphe nucleus was stimulated, rodents facing a challenge in the lab showed an immediate and dramatic surge in motivation.
Effect of xanthone from Kielmeyera coriacea stems on serotonergic neurons of the median raphe nucleus.
Lower brainstem catecholamine afferents to the rat dorsal raphe nucleus.