2] This type of rearrangement
takes place during meiosis I and involves formation of a hexavalent configuration that allows the full synapsis of homologous segments.
The leukemia cells of up to 80 percent of infants with ALL have a chromosomal rearrangement
that fuses the MLL gene to a gene on a different chromosome.
Validation of immunoglobulin gene rearrangement
detection by PCR using commercially available BIOMED-2 primers.
Online Supplemental Table 2 illustrates the additional data-filtering steps for the detection of DNA fragments harboring structural rearrangement
The Mitelman lymphoma database in 2009 reported only eight triple-hit lymphomas out of 796 lymphomas containing a BCL-6 gene rearrangement
This Lewis acid catalyzed rearrangement
offers several advantages over current technology: 1) it lends itself towards developing an asymmetric variant of this transformation via the use of a chiral Lewis acid or a metal salt with chiral ligand additives, 2) the exclusion of n-BuLi to promote the reaction will result in a broader substrate scope by allowing acidic or electrophilic functional groups to be present in the molecule, and 3) this rearrangement
is an environmentally friendly alternative to the Overman rearrangement
7,10,11) ERG rearrangements
appear highly clonal because, when present, nearly all cells in a given cancer focus are positive, although distinct cancer foci in a single prostate may have discordant ERG rearrangement
The purpose of this article is to exhibit an alphabetic rearrangement
(not unique) that minimizes the number of three-letter Official Scrabble Players Dictionary heterograms.
If the genome were like a book with many chapters, the rearrangement
would be like swapping of two chapters within book, so that both chapters would be out of order.
The method his colleagues reported last month is more thorough, since the rearrangement
is likely to occur in every cancer cell in the patient's body.
Just as important, the genomes were different from each other, with multiple distinctive patterns of rearrangement
observed, supporting the view that breast cancer is not one, but several diseases.
of the visit to Carlisle, postponed last Saturday, for February 10, has already left Walsall facing fixtures on three successive Tuesday nights.