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As the duration of breath holding during pranayama is gradually increased by the practice of pranayama so that the respiratory center is acclimatized to withstand higher and higher carbon-di-oxide concentrations in the alveoli and the blood.
Respiratory centers were affected, as were vegetative nucleates of the medulla oblongata (Figure 1).
However, antidepressants or other drugs aimed at altering the activation of the respiratory centers in the brain and CPAP therapy or apnea surgery aimed at correcting the anatomical problems involved in sleep-disordered breathing have had inconsistent or results.