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It is the most severe form, because the salt wasting occurs in numerous mineralocorticoid-sensitive tissues, including the lungs, kidneys, colon, and sweat and salivary glands.
Hyponatremia in the postoperative craniofacial pediatric patient population: a connection to cerebral salt wasting syndrome and management of the disorder.
Hyponatremia in a neurosurgical patient: Syndrome of inappropriate antidiuretic hormone secretion versus cerebral salt wasting.
Predicted clinical Mutation group (a) phenotype of CAH Genotype (b) Null Salt wasting Del/Del Q318X/(Q318X, Del) R356W/(R356W, Del) E6 cluster/(E6 cluster, Del) R356W/Del 8 bp Total (c) A Salt wasting I2 G/(I2 G, Del) I2 G/R356W I2 G/E6 cluster I2 G/Del 8 bp Total (c) B Simple virilizing I172N/I2 G I172N/(I172N, Del) Total (c) C Nonclassical P30L/I2 G P30L/(P30L, Del) P453S/I2 G Total (c) No.
Fifty-eight patients suffered from the salt wasting form; 27 suffered from the simple virilizing form; and 6 suffered from the nonclassical form.