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saturate |
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The binding of brevetoxin to HDL was reversible and saturable, as it was inhibited by 40% [+ or -] 7% in the presence of 50 [micro]M unlabeled PbTx-3. Clearance of FG-3019 was saturable, and accumulation of FG-3019 in the bloodstream was limited during the dosing interval. Thus, binding is saturable, and equilibrium may be described by the law of mass action (Krauer et al. |
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