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sedative |
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Seeburg and his colleagues at the University of Heidelberg in Germany have identified a molecule on the surface of nerve cells that responds abnormally to the sedative drug diazepam, better known by the trade name Valium. Compared to standard clinical practice, however, BIS-guided sedative dosing to an average BIS value of 72 resulted in only a small reduction in patient recovery time and the average administered dose of propofol, a commonly used sedative drug. Our study showed that by using BIS as an objective measure of sedation, we could safely reduce the amount of sedative drug we were giving most patients. |
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