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Related to sickle cell disease: sickle cell trait, Sickle cell crisis
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Novel Therapy Decreases Red Blood Cell Sickling in Patients with Sickle Cell Disease GBT440, a Potent Anti-Sickling Hemoglobin Modifier Reduces Hemolysis, Improves Anemia and Nearly Eliminates Sickle Cells in Peripheral Blood of Patients with Sickle Cell Disease [542]
Sickle cell anaemia is the most common sickle cell disease and is caused by abnormal haemoglobin that cause a rigid, distorted and sickle-shaped red blood cell.
Studies suggest that about 10% of children with sickle cell disease will have a clinically evident stroke unless they get prophylactic therapy and up to 35% will have silent infarctions.
The findings have suggested that children with or without sickle cell disease who have acute anemia could be suffering undetected brain damage.
Bahrain's efforts at preventing sickle cell disease have been recognised worldwide but we still have a problem with management," Dr Al Arrayed told the GDN.
One of the most common genetic disorders, sickle cell disease causes blood cells to take the shape of a crescent instead of being smooth and round, thereby blocking blood flow and leading to chronic pain, infections and tissue death.
She said the high incidence of sickle cell disease in Bahrain could be blamed on a series of malaria attacks, including the one in the 1930s.
It comes after 65 per cent of A&E staff revealed they did not have enough information to provide the right care for people with sickle cell disease, even though most casualty departments see someone with the disease six times a year.
This summer, Britain will launch a new code for the clinical care of Sickle Cell Disease in the country.
ATLANTA -- Neuropsychological dysfunction and undetected brain injury affect the majority of adults with sickle cell disease, even though they are neurologically intact, according to research presented at the annual meeting of the American Society of Hematology.
In 2001, we conducted a survey of Ugandan children with sickle cell disease and their mothers and found that human herpesvirus 8 infection was associated with transfusion in these children (5).

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