Mutation

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Related to somatic mutation: Somatic hypermutation

MUTATION, French law. This term is synonymous with change, and is particularly applied to designate the change which takes place in the property of a thing in its transmission from one person to another; permutation therefore happens when, the owner of the thing sells, exchanges or gives it. It is nearly synonymous with transfer. (q.v.) Merl. Repert. h.t.

References in periodicals archive ?
speculated that somatic mutation in SWS might occur earlier in development, in progenitor cells that were precursors to a larger variety of cell types and tissues, leading to the syndromic phenotype.
Targeted next generation sequencing (NGS) enables detection of low-frequency somatic mutations (i.
The somatic mutation data were obtained using whole-exome sequencing and are shown in the form of a mutation annotation format (MAF) file.
Somatic mutations of TP53 are associated with more advanced stages of the disease, with loss of TP53 gene heterozygosity being a marker for the conversion of adenoma to carcinoma.
5 as sectorial NF, who proposed that such neurofibromatosis limited to a distinct sector of the body, without genetic transmission of the trait could be explained by somatic mutation.
This innovative assay goes beyond limitations of standard array comparative genomic hybridization methods to yield copy number, allelic ratio, and somatic mutation data from only 75 nanograms of input DNA, the lowest sample requirement available.
The list of diseases attributable to somatic mutation is growing rapidly.
It is certainly biologically plausible that host factors other than specific tumour-acquired factors (altered protein function due to somatic mutation, loss of function or altered levels of expression) may affect outcome.
In contrast, off-types in cultivars Tifgreen and Tifdwarf resulted predominantly from genetic instabilities arising from somatic mutation but not from gross chromosomal rearrangements.
A somatic mutation is a genetic mutation in one, several or many of the individual's cells.
McKusick suggests that the dwarf twin might have resulted from a so-called somatic mutation in one cell after the two twins had separated.