2,3,5,6) Additionally, Pansuriya and coworkers recently found that there are also mutations in the gene encoding isocitrate dehydrogenase 1 and 2 in enchondromas and spindle cell
Benign and malignant spindle cell
lesions of the breast.
Histologically, the nodule comprised a mixture of spindle cells
that resembled ovarian stroma and tubular elements lined by flattened epithelium with eosinophilic cytoplasm (Figure 1b).
Cytologically, nodular fasciitis can be easily mistaken for a malignant neoplasm of spindle cells
or a tumor of salivary gland origin.
Cellular angiofibroma: analysis of 25 cases emphasizing its relationship to spindle cell
lipoma and mammary-type myofibroblastoma.
In general, melanoma tumour cells are about 95% immunoreactive to S-100, including the spindle cell
In an attempt to further characterize the spindle cell
sarcoma mass, immunohistochemical analysis was performed for osteocalcin and osteonectin.
Three main histopathologic patterns of IMT have been described: (1) a myxoid/vascular pattern (Figure 2, A) characterized by spindle/stellate myofibroblasts with abundant eosinophilic cytoplasm and vesicular nuclei; (2) a compact, spindle cell
proliferation (Figure 2, B)--sometimes with some ganglion-like cells--arranged in fascicular or storiform patterns, with varying degrees of cellularity; and (3) a hypocellular, fibrous pattern (Figure 2, C), displaying abundant collagen, plasma cells, lymphocytes, and eosinophils (similar to desmoid fibromatosis).
Microscopy showed spindle cells
arranged in short fascicles and sheets.
In these lesions, a solid spindle cell
KS proliferation is exclusively intravascular .
Members learned and practised aspects of working with spindle cells
in the belly of muscles and with the Golgi apparatus, designed to achieve good results with minimum discomfort.
Squamous differentiation and spindle cell
areas were not identified (Fig.