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Actually, this pathotype is heterogeneous regarding the presence of putative virulence genes and has recently been subgrouped into typical and atypical EAEC, which carry and lack AggR (a global regulator of EAEC virulence), respectively (1,3). Figure 6A shows the mean ANA titers for the Libby samples when subgrouped by duration of exposure and demonstrates that the titers were significantly higher for those subjects exposed to asbestos for > 5 years. Subjects in the intervention group were subgrouped into those attending 1 to 6 treatment sessions, those attending 7 to 12 treatment sessions, and those attending >12 treatment sessions. |
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