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substance
(redirected from substance P)

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Encyclopedia, Wikipedia 0.02 sec.

Essence; the material or necessary component of something.

A matter of substance, as distinguished from a matter of form, with respect to pleadings, affidavits, indictments, and other legal instruments, entails the essential sufficiency, validity, or merits of the instrument, as opposed to its method or style.


substance (Essential nature), noun actuality, basis, body, content, core, drift, essence, essential part, force, gist, heart, hypostasis, idea, import, marrow, material, meaning, pith, principle, purport, reality, res, sense, significance, signification, soul, sum, tenor, vital part
substance (Material possessions), noun assets, command of money, corpus, estate, fortune, income, means, money, ownership, property, resources, revenue, riches, treasure, wealth, wherewithal
See also: amount, article, body, bulk, capsule, center, composition, connotation, consequence, construction, content, contents, contour, cornerstone, corpus, element, essence, gist, gravamen, import, importance, main point, materiality, meaning, money, object, point, possessions, property, purpose, quantity, reality, shape, significance, signification, spirit, structure, sum, value

SUBSTANCE, evidence. That which is essential; it is used in opposition to form.
     2. It is a general rule, that on any issue it is sufficient to prove the substance of the issue. For example, in a case where the defendant pleaded payment of the principal sum and all interest due, and it appeared in evidence that a gross sum was paid, not amounting to the full interest, but accepted by the plaintiff as full payment, the proof was held to be sufficient. 2 Str. 690; 1 Phil. Ev. 161.



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Basbaum, a neuroscientist at the University of California, San Francisco, studied the distribution of substance P and its receptor molecules in the spinal cord.
The peripheral neurons that release substance P are thought to send pain signals to the brain and to help regulate the immune response in damaged tissues.
Compounds that moderate Substance P not only moderate pain, but also reduce the inflammation that exacerbates many ailments, such as arthritis and asthma.
 
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