In the current paper, the scientists studied taste organoids at different stages of growth to identify the genes turned on at each stage of taste cell
Some scientists have also found taste cells
along the path that food travels through a person's body--a journey of at least 12 hours.
Further, selective stimulation of the taste cells
expressing T2Rs is sufficient to elicit a strong aversive response in mice (Mueller et al.
Future studies will focus on identifying the factors that program the Lgr5-expressing cells to differentiate into the different taste cell
types, and explore how to grow these cells in culture, thus providing a renewable source of taste receptor cells for research and perhaps even clinical use.
When hit by bitter--potentially toxic--substances, gut taste cells
sound an alarm that may lead to slower absorption or spur vomiting.
One of the Nature papers described the surprising discovery that the retinal protein transducin is present in taste cells
The authors speculate that KATP may function in sweet taste cells
to modulate taste cell
sensitivity to sugars according to metabolic needs.
The work confirms earlier findings by others that chloride diffuses into taste buds through a dense network of filaments that swathe taste cells
and link them to one another.
Adenosine receptors are expressed in sweet-sensitive taste cells
Because sour taste is the perception of acidic substances, which have a high concentration of protons, Liman predicted that sour taste cells
have an ion channel that responds to or transports protons.
Each taste bud contains 50 to 100 taste cells
, which contain molecules, known as receptors.
Sense of sweetness is transferred through receptors on specialized taste cells