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a member of the Daiichi Sankyo Group, announced today that The New England Journal of Medicine (NEJM) published clinical trial results demonstrating that the investigational drug, PLX3397, an oral targeted CSF-1R inhibitor, induced prolonged tumor regressions in most patients with tenosynovial giant cell tumor (TGCT), a rare, locally aggressive neoplasm of the joint or tendon sheath.
They can also efficiently inoculate small joints, deep spaces, or tendon sheaths of the hand.
4) Many authors subsequently reported that he "overstated" their biologic potential by calling them "cancers of the tendon sheath.
Loose bodies develop as a result of the proliferation and fragmentation of the synovial lining of the joint, bursa or tendon sheath.
She also feels grateful to be back onstage after a tendon sheath injury on her first tour with the company in September 2011.
Aside from its intra-articular location, it otherwise had the morphologic attributes of a giant cell tumor of tendon sheath GCTTS.
The flexor pulley system is composed of focal thickened areas of the flexor tendon sheath (1).
Ganglions are mucinous-filled cysts arising from a joint capsule or tendon sheath.
There are also several reports of fibroma of the tendon sheath which is distinct from the tendon.
In the operating room he underwent incision and drainage of the left ring finger, flexor tendon sheath and palm with tenosynovectomy.
On day 7 in HA group the tendon sheath showed granulation reaction characterized by large number of intermingled plump shaped fibroblasts aligned concentrically around the tendon fascicles (Fig.
By the time he saw Weiland in August he had little option but to go under the knife to repair a torn tendon sheath.