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thalamus |
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vulnificus infection, including chronic liver disease (30%), chronic renal failure (15%), diabetes mellitus (7%), and thalassemia major (3%). Yersiniae have an impaired iron metabolism, and for this reason, they rarely cause sepsis in patients without iron overload, which is often secondary to alcoholism, asplenia, hemochromatosis, thalassemia major, or tobacco smoking (1). Pegasys and Copegus therapy is additionally contraindicated in women who are pregnant, men whose female partners are pregnant, and patients with hemoglobinopathies (eg, thalassemia major, sickle-cell anemia). |
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