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We performed a double-blind randomised controlled trial comparing these two practices to test the hypothesis that intraoperative intravenous administration of paracetamol would be more effective in achieving potentially therapeutic plasma concentrations in the early postoperative period than the same dose given orally preoperatively.
Higher concentrations of solution, longer nebulization periods, or more frequent administration are likely needed to reach therapeutic plasma concentrations of terbinafine for clinically relevant periods in Hispaniolan Amazon parrots.
We wished to establish whether the IV preparation, the oral preparation or both achieve therapeutic plasma concentrations perioperatively and if so, for how long these are maintained and what maximum plasma concentrations are achieved.

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